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pentobarbital will lower the level or impact of mestranol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.pentobarbital will reduce the extent or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Potent CYP3A4 inducers are anticipated to result in signific